Antioxidative function of L-FABP in L-FABP stably transfected Chang liver cells
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منابع مشابه
L-FABP and I-FABP expression increase NBD-stearate uptake and cytoplasmic diffusion in L cells.
The effects of intestinal and liver fatty acid binding protein (I- and L-FABP, respectively) expression on single-cell fatty acid uptake, internalization, and cytoplasmic diffusion were determined in transfected L cell fibroblasts. These parameters were measured using the nonesterifiable fluorescent fatty acid probe 12- N-methyl-(7-nitrobenz-2-oxa-1,3-diazol)aminostearate (NBD-stearate) and flu...
متن کاملSusceptibility of L-FABP-/- mice to oxidative stress in early-stage alcoholic liver.
Chronic ethanol consumption is a prominent cause of liver disease worldwide. Dysregulation of an important lipid uptake and trafficking gene, liver-fatty acid binding protein (L-FABP), may contribute to alterations in lipid homeostasis during early-stage alcoholic liver. We have reported the detrimental effects of ethanol on the expression of L-FABP and hypothesize this may deleteriously impact...
متن کاملL-FABP and I-FABP expression in newborn rats changes inversely in the model of necrotizing enterocolitis.
PURPOSE To determine the expression of hepatic L-FABP and intestinal I-FABP in an experimental model of necrotizing enterocolitis (NEC) in neonatal rats. METHODS Newborn Sprague-Dawley rats were divided into four groups: Control (C1) - exclusive breastfeeding at the first and sixth procedures (C6), NEC1 - fed formula milk and submitted to hypoxia and hypothermia at the first and sixth procedu...
متن کاملLiver fatty acid-binding protein (L-FABP) promotes cellular angiogenesis and migration in hepatocellular carcinoma
Liver fatty acid-binding protein (L-FABP) is abundant in hepatocytes and known to be involved in lipid metabolism. Overexpression of L-FABP has been reported in various cancers; however, its role in hepatocellular carcinoma (HCC) remains unclear. In this study, we investigated L-FABP and its association with vascular endothelial growth factors (VEGFs) in 90 HCC patients. We found that L-FABP wa...
متن کاملLiver Type Fatty Acid Binding Protein (L-FABP): A Marker of Contrast Induced -Acute Kidney Injury
Background: Urinary Liver type fatty acid binding protein (L-FABP) is an early biomarker for renal damage. A few studies have been published analyzing the potential use of urinary Liver type fatty acid binding protein (L-FABP) as a biomarker for acute kidney injury. However no study has been done related to Acute Kidney Injury associated with contrast administration. Aim: To search for new mark...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2005
ISSN: 0270-9139,1527-3350
DOI: 10.1002/hep.20857